Expression Pattern of Stemness-Related Genes in Human Endometrial and Endometriotic Tissues

Amalia Forte, Maria Teresa Schettino, Mauro Finicelli, Marilena Cipollaro, Nicola Colacurci, Luigi Cobellis, and Umberto Galderisi
 
Endometriosis is an estrogen-dependent disease that affects 5 to 10% of women of reproductive age in the Western countries. In this study, Forte et al. examined the expression of embryonic stemness-related genes in human normal endometrium and pathological endometriotic samples. The authors found increased expression profiles of several genes in endometriosis as compared with normal endometrium. Based on these observations, the authors suggest that stem cells may play a role in the pathogenesis of endometriosis.

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Posted by MolMed Editor on Nov 4, 2009 12:00 AM CST