The Pathogenesis of Lyme Neuroborreliosis – From Infection to Inflammation

Review Article

Tobias A Rupprecht, Uwe Koedel, Volker Fingerle, and Hans-Walter Pfister


Lyme borreliosis is the most common human tick-borne disease in the Northern hemisphere. It is caused by the spirochete Borrelia burgdorferi which enters the host through a tick bite on the skin. In this review, Rupprecht et al. (205-212) describe current knowledge regarding the pathogenesis of acute Lyme neuroborreliosis (LNB), from invasion to inflammation of the central system.

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Posted by Leah Caracappa on Apr 6, 2008 12:00 AM CDT