Novel Therapeutic Strategies for Brain Tumors

One novel therapeutic approach targets the stimulatory role of microglia in the malignant behavior of glioblastoma tumors. Preclinical experiments showing radio-sensitization of glioblastoma tumors by semapimod, an anti-inflammatory drug, will be discussed. A second approach focuses on the identification of radio-sensitization drugs in medulloblastoma, with the goal of diminishing long term side-effects of radiation treatment.

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